BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

The fibroblasts were directly converted into iPULs (induced pulmonary epithelial-like cells)—functionally akin to native AT2 ...

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse ...

Pancreatic cancer is one of the most lethal cancers, with only about 12% of patients surviving five years after diagnosis. A ...

A recent study showed that the differentiation of fibroblasts in the sublining of the synovium of the rheumatoid joint capsule is influenced by the vascular endothelium and implicates the Notch3 ...

Trisomy is a genetic condition characterized by the presence of an extra chromosome. This means that the affected person has ...

The main function of fibroblasts is to produce the extracellular matrix and collagen needed for animal tissues.

Fibroblasts are an important component of the tumour microenvironment. They become activated in tumours, as they do in healing wounds. Here, their roles in tumour initiation, progression and ...

Volar injections made thigh skin thicker. This therapy could potentially help prevent pressure-induced skin damage in patients using prosthetics.

Researchers have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic ...

Fibroblasts reprogrammed into AT2-like lung cells in just 7–10 days, offering a faster, safer alternative to stem cell therapy for lung disease.