Basic Science The esterase method of detecting leukocytes in a urine sample relies on the fact that esterases are released from lysed urine granulocytes (neutrophils). In the dipstick method ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

Background Early-life inflammation has long been recognised as a key pathophysiological process in the evolution of cystic ...

Endosomal recycling is a branch of intracellular membrane trafficking that retrieves endocytosed cargo proteins from early and late endosomes to prevent their degradatio ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

LV thrombi were successfully lysed in 10 of 16 patients. None of the patients suffered from clinical embolism, and therapy had to be discontinued in only one patient due to haematuria. w33 In a later ...

For use with our PCR rapid detection systems, BIOTECON Diagnostics has developed fast and easy-to-use DNA extraction kits. The foodproof ® ShortPrep, StarPrep, Sample Preparation and Magnetic ...

Antibodies were incubated with Dynabeads protein G (Invitrogen, Carlsbad, US) at 4°C for at least 30 minutes. Cells were lysed in NP-40 buffer (Beyotime, Shanghai, China) supplemented with protease ...

MSC senescence is considered a contributing factor in aging-related diseases. We investigated the influence of the inflammatory microenvironment on bone marrow mesenchymal stem cells (BMSCs) under ...