Subsequent OCBs, AQP4 and anti-MOG antibodies proved negative, whereas bone marrow sampling demonstrated evidence of haematological disease progression. A repeat MRI was strikingly abnormal with ...
The comparison of OCB in serum and CSF allows the distinction of 5 patterns (24, 25): absence of OCB in both CSF and serum (type 1, no immune activation), presence of OCB in CSF but not in serum (type ...