2006). Oblimersen, an 18-mer phosphorothioate Bcl-2 mRNA anti-sense, anneals to the initiation codon region of Bcl-2 mRNA, thereby inhibiting Bcl-2 biosynthesis (Fulda et al., 2010). Oblimersen was ...

State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Molecular Recognition and Biosensing, Frontiers Science Centers for Cell Responses and New Organic Matter, College of ...

Myotonic dystrophy type 1 (DM1) is the most common muscular dystrophy that affects multiple systems including the muscle and heart. The mutant CTG expansion at the 3′-UTR of the DMPK gene causes the ...

Gansu International Scientific and Technological Cooperation Base of Water-Retention Chemical Functional Materials, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou ...