Psoriatic arthritis (PsA) has historically been considered a milder rheumatic disease not yielding significant clinical damage. However, recent studies have shown that PsA can be deforming and ...

Objective: To compare the efficacy of aerobic walking and home based quadriceps strengthening exercises in patients with knee osteoarthritis. Methods: The Medline, Pubmed, EMBASE, CINAHL, and PEDro ...

Objective To compare the relative bioavailability, safety and tolerability of oral methotrexate (MTX) and subcutaneous (SC) MTX administered via an auto-injector (MTXAI) in patients with rheumatoid ...

Methods: This is a multicenter, randomized, double-blind, active-controlled, parallel-group, Phase 3 study (NCT05007392). Gout subjects with serum uric acid (SUA) level >7.0 mg/dL were randomized into ...

Chimeric antigen receptors (CARs) are synthetic proteins designed to direct an immune response toward a specific target and have been used in immunotherapeutic applications through the adoptive ...

IgG4-related disease (IgG4-RD) can cause fibroinflammatory lesions in nearly any organ. Correlation among clinical, serological, radiological and pathological data is required for diagnosis. This work ...

Raynaud’s phenomenon (RP) with or without digital ulcer formation is a significant cause of morbidity for patients with systemic sclerosis (SSc, scleroderma). Lichtenstein reported oral sildenafil as ...

The nephroprotective efficacy of sodium-glucose cotransporter-2 (SGLT-2) inhibitors (SGLT-2i) in patients with chronic kidney disease, with or without type 2 diabetes, has already been described.1 ...

A century ago syphilis was regarded as the great masquerader. Its modern equivalent is lupus. It may present to a wide range of specialists and its outcome, while much improved, remains uncertain in a ...

Results This study included 17,756 new users of pregabalin and 221,053 new users of gabapentin. The cohort was predominantly female gender (66.7%), and non-Hispanic White (79.9%), with a median age of ...

Background Fibromyalgia (FM) is a common chronic disorder characterized by widespread pain, fatigue, sleep disturbances and functional symptoms, reaching a prevalence of 2–3% worldwide. It can present ...

Gout is the most common inflammatory arthritis and one in which pathogenesis and risk factors are best understood. One of the treatment objectives in current guidelines is ‘cure’. However, audits show ...