Background Antimicrobial resistance (AMR) is a growing global health crisis and is particularly relevant to people living ...

Objective Long-term azithromycin treatment effectively prevents acute exacerbations of chronic obstructive pulmonary disease ...

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COPD is a progressive disease where airway inflammation plays an important part. Previously, there were large expectations that regular anti-inflammatory treatment with inhaled corticosteroids (ICS) ...

Methods Pre-clinical work captured clinically relevant extremes of respiratory parameters using a pediatric mannequin and mechanical ventilation. Biosensor data was compared to ventilator-measured ...

Background Coding practices impact the recorded prevalence of disease. Sepsis, most commonly caused by pneumonia, remains a common cause of mortality worldwide. In April 2017, NHS Digital issued new ...

The 2020 coronavirus pandemic has been particularly difficult for people living with chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD). COPD is associated with ...

Method Adults with a first-recorded code for breathlessness (index date) and subsequent coded diagnosis between 2007 and 2017 were included from a UK primary care database (CPRD-GOLD). Cox regression ...

Reduction of the risk of asthma attacks is a major goal of current asthma management. We propose to derive a risk scale predicting asthma attacks based on the blood eosinophil count and exhaled nitric ...

Background No prior study has examined the effects of air pollution on the progression from healthy to chronic lung disease, subsequent chronic lung multimorbidity and further to death. Methods We ...

Introduction Chronic rhinosinusitis with nasal polyposis (CRSwNP) affects a significant proportion of people with severe asthma (SA). Despite the effectiveness of anti-IL5/5R therapies in the ...