Syphilis is one of the oldest known diseases. Approximately 209,000 cases were reported in the United States in 2023 — the highest number of reported cases since 1950 — including nearly 4000 ...

To the Editor: The BROADWAY trial by Nicholls and colleagues (July 3 issue) 1 was a pivotal evaluation of an intriguing agent. However, I am concerned about the use of placebo in patients with ...

Patients benefit from antiplatelet therapy after coronary-artery bypass grafting (CABG) for an acute coronary syndrome.

Poorly controlled hypertension is a common problem worldwide, particularly in low-resource settings. We conducted an ...

An appropriate duration of dual antiplatelet therapy after percutaneous coronary intervention for acute myocardial infarction ...

China has recently emerged as an important player in new drug development — a field traditionally dominated by the United States and Europe. This shift has implications for global access to new ...

Mavacamten is approved to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM). However, its effects ...

Beta-blockers have been the initial treatment for symptomatic obstructive hypertrophic cardiomyopathy (HCM) despite limited ...

Hosted by Arjun (Raj) Manrai, Ph.D. and Andrew Beam, Ph.D., NEJM AI Grand Rounds features informal conversations with a variety of unique experts exploring the deep issues at the intersection of ...

A rare T-cell lymphoma after chimeric antigen receptor (CAR) T-cell therapy for myeloma was linked to CCR4 overexpression and vector integration, which highlights the need for monitoring after CAR ...

The inherent variability and potential inaccuracies of AI-generated output can leave even experienced clinicians uncertain about AI recommendations. This dilemma is not novel; it mirrors the broader ...

This review discusses the global clinical burden and consequences of MASLD as a multisystem disease, briefly describing the natural history, pathophysiology, risk stratification, and case finding of ...