Among patients with severe hemophilia A and B, treatment with the monoclonal antibody marstacimab has been associated with reduced rates of bleeding, according to a systemic review and meta-analysis ...

Updated guidelines for managing patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) from the British Society for Rheumatology (BSR) were published recently in ...

A CRISPR/Cas9-modified Janus kinase 2 (JAK2) V617F model may be useful to develop new therapies against myeloproliferative neoplasms (MPNs), showed a new study published in the International Journal ...

Spesolimab demonstrates promising real-world efficacy in treating generalized pustular psoriasis (GPP), according to a recent review published in Clinical and Experimental Dermatology. More than half ...

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a disorder characterized by progressive, symmetrical muscle weakness and disturbances in the distal upper and lower extremities. While it is ...

In patients with suspected IgG4-RD, a diagnosis typically takes some time, involving physical examination, imaging, laboratory testing, and pathology. The tumefactive lesions that are the hallmark of ...

The investigational mRNA therapeutic IN013 received both Rare Pediatric Disease Designation and Orphan Drug Designation from the US Food and Drug Administration for the treatment of Wilson disease (WD ...

Enrollment is under way to recruit patients for a phase 3 study designed to assess intravascular (IV) treatment with zaltenibart among individuals with paroxysmal nocturnal hemoglobinuria (PNH), ...

The CSHA Clinical Frailty Scale (CFS) is a valuable tool for predicting treatment-related toxicity and discontinuation in older adults receiving targeted therapy for chronic lymphocytic leukemia (CLL) ...

For patients with eosinophilic granulomatosis with polyangiitis (EGPA)—a type of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) that is mediated largely by ...

A male patient initially suspected of having immunoglobulin G4-related disease (IgG4-RD) had his diagnosis revised to Castleman disease following further investigations. This case report was published ...

The presence of anti-myelin oligodendrocyte glycoprotein (MOG) antibodies in patients with anti-aquaporin 4 (AQP4) antibody-negative neuromyelitis optica spectrum disorder (NMOSD) is key for accurate ...