RGN-259 is a thymosin beta-4–based eye drop designed to rival Dompé’s Oxervate, the only FDA-approved prescription eye drop ...

Thymosin β4 is unique, because oxidation attenuates its intracellular G-actin sequestering activity 7, but greatly enhances its extracellular signaling properties.

Thymosin β4 (Tβ4) is a short peptide known for its key role in tissue repair and angiogenesis. In this study, we successfully developed a multifunctional injectable Exo@Tβ4/HAMA hydrogel platform by ...