Researchers have found that cannabidiol (CBD) significantly reduces seizures and extends survival in a mouse model of ...

Guidance from the American Academy of Pediatrics covers multiple genetic testing approaches to diagnosing developmental delay ...

In a clinical report issued by the American Academy of Pediatrics and published online June 23 in Pediatrics, guidance is ...

In a clinical report issued by the American Academy of Pediatrics and published online June 23 in Pediatrics, guidance is ...

MID1 in Huntington’s Disease MID1 and CAG Repeats CAG repeat expansion diseases including HD represent one of the most common forms of inherited neurodegeneration. The expansion mutation of the ...

近日，悦康药业集团子公司北京悦康科创医药科技股份有限公司在材料科学领域的 国际权威期刊 《 Journal of Materials Chemistry B 》 在线发表题为 “ GPT-driven generation and biological activity evaluation of novel mRNA trinucleotide Cap1 analogs for mRNA vac ...

The secondary structure of repeated trinucleotide sequences results in the development of several neurodegenerative diseases, and these studies consider the (CAG)8 sequence that forms a stem−loop ...

Discussion Ataxia with oculomotor apraxia is an autosomal recessive disease, originally described in Portuguese patients and later in Japanese patients. Symptoms first noticed appear between ages ...

Many neurological diseases are caused by pathogenic unstable intragenic trinucleotide repeat (TNR) expansions, such as the GAA trinucleotide repeat within the FXN gene in Friedreich ataxia (FRDA ...

The reaction of low-energy electrons (LEEs; 10 eV) with 5′-TpXpT-3′ (TXT), where X is uracil (U), thymine (T), and 5-bromouracil (5BrU), was examined by HPLC-UV analysis. The presence of 5BrU ...

The subcellular localization of long non-coding RNAs (lncRNAs) is fundamental to understanding their functional roles in gene regulation and disease mechanisms. Existing prediction models typically ...