Mouse osteopontin ELISA kit is a method for quantitative determination of OPN (osteopontin) in mouse plasma, urine and cell culture media. This assay has a minimum sensitivity detection limit of 0.15 ng/ml.

2018年1月1日 · Osteopontin is predominantly expressed by cerebral-infiltrating monocytes and macrophages tightly associated with Aβ plaque. Upregulation of osteopontin in macrophages was achieved by glatiramer acetate. Phagocytosis of fibrillar Aβ is OPN dependent. OPN mediates macrophage polarization towards the anti-inflammatory phenotype.

4 天之前 · Alzheimer's mice exhibit increased expression of SPP1/OPN and CSF-1 c compared to wild-type mice; Microglia: Amyloid beta: Wang et al. (2020) In vivo: 5XFAD mice. In vitro: bone marrow macrophage. Experimental: 5XFAD mice: Brain: Systemic administration of AL002c (TREM2 agonist) AD mice showed elevated expression of SPP1/OPN and CSF-1 c

2021年12月8日 · We examined, if the level of OPN in the cerebrospinal fluid (CSF) and blood is associated with late-time regional brain volumes and white matter (WM) lesion load in MS. Concentrations of OPN in...

The Mouse Osteopontin (OPN/SPP1) ELISA quantitates Ms OPN in mouse serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Ms OPN. The Mouse OPN solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair.

The Mouse Osteopontin (OPN/SPP1) ELISA quantitates Ms OPN in mouse serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Ms OPN. The Mouse OPN solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair.

Osteopontin (OPN) is a secreted glycoprotein that was originally isolated from bone. At present, it is known as a highly acidic calcium-binding glycosylated phosphoprotein secreted by many cell types, including osteoblasts, kidney tubule cells, macrophages, activated T cells, and vascular smooth muscle cells.

ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Osteopontin are available for Human, Mouse and Rat which can be quantified in various samples, including plasma, serum, supernatant. Invitrogen ELISA …