Potential role of leonurine in cardiovascular disease. Leonurine can treat cardiovascular disease by anti‐atherosclerosis, reducing myocardial infarction and cardioprotective effects. It plays a strong protective role through a wide range of mechanisms.

Leonurine is the main active alkaloid isolated from the traditional herb Leonuri Herba and exhibits multiple pharmacological functions, such as hypolipidemic, anti-platelet aggregation, anti-inflammatory, analgesic, anti-oxidative stress, and anti-fibrotic effects [113]. From: Biomedicine & Pharmacotherapy, 2023

Leonurine | C14H21N3O5 | CID 161464 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

2024年7月19日 · This paper summarizes the extraction methods, synthetic pathways, biosynthetic mechanisms, pharmacokinetic properties, pharmacological effects in various diseases, toxicology, and clinical trials of leonurine.

Leonurus japonicus Houtt, a Chinese traditional herbal medicine, has been widely used to cure gynecological diseases, such as incomplete abortion and menoxenia. Leonurine, a major active alkaloid compound only be found in Leonurus japonicus Houtt, has …

This paper reviews the potential therapeutic effects of leonurine on cardiovascular system and central nervous system diseases, summarizes the previous research progress, and focuses on its therapeutic effect in various diseases.

2024年7月18日 · Leonurine is an alkaloid unique to the Leonurus genus, which has many biological activities, such as uterine contraction, anti-inflammation, anti-oxidation, regulation of cell apoptosis, anti-tumor, angiogenesis, anti-platelet aggregation, and inhibition of vasoconstriction.

2024年1月1日 · Leonurine, the principal active compound found in Leonurus, has demonstrated promising effects in reducing blood lipids and treating strokes. However, the biosynthetic pathway of leonurine remains largely unexplored.

2018年5月29日 · Leonurine, a specific component of H. leonuri, has been reported to reveal cardio-protective effects in vivo and in vitro (9,10). Leonurine's effects also result in increased phosphorylation of AKT and expression of HIF-1, Surviving and VEGF in …

2018年8月1日 · Leonurine is the main active compound of motherwort, and first time we had uncovered the cardiovascular protection of leonurine through the anti-apoptotic and anti-inflammatory effects in the past several decades.