The aim of this study is to determine the efficacy and safety of the sclerosant polidocanol - which is a well-known detergent-type sclerosing agent - in foam form compared with liquid form. Methods: A total of 100 women patients with telengiectases and small varicose veins of less than 4 mm were included in this study.

We reviewed in-vitro, Phase I, Phase II and limited Phase III data for polidocanol microfoam with a focus on controlled foam formulation in therapy. Clinical trials of controlled dispensing of polidocanol microfoam provide evidence of effective treatment of chronic venous insufficiency with low toxicity, minimal risk and few complications.

Sclerotherapy is the targeted chemical ablation of a varicose vein by intravenous injection of a liquid or foam sclerosant [1, 2]. Intradermal, subcutaneous and/or transfascial (perforator) veins can be treated by this method, as well as epi-, supra- …

Sclerotherapy with polidocanol foam effectively achieved CR and PR in patients without any severe complications. However, the present study did not include cases involving infants. Thus, further studies are required to explore the efficacy and safety of …

Polidocanol foam sclerotherapy (PFS) is associated with a low rate of bleeding complications. The aim of this study was to compare the efficacy and safety of PFS in the treatment of HD in patients with and without BD.

2022年10月21日 · Sclerotherapy with 3% polidocanol foam is becoming increasingly popular for the treatment of symptomatic I–II or III degree haemorrhoidal disease (HD). However, there are no studies that have reported a follow-up of more than 1 year.

Surgical treatment and foam sclerotherapy achieved high rates of ulcer healing, without a statistically significant difference. Both treatments led to significant improvements in VCSS, VDS, AVVQ scores, demonstrating improvements in clinical outcomes and quality of life.

2024年1月23日 · To evaluate the safety and efficacy of bleomycin polidocanol foam (BPF) sclerotherapy for venous malformations (VMs) and analyze the associated clinical outcomes and predictors.

2006年1月1日 · The results of this study show that for the same concentration of polidocanol, the efficacy of sclerotherapy with foam is greater than with liquid, although risks of minor adverse effects such as pain, inflammation, and skin pigmentation are also more frequent.

2025年1月29日 · All patients who presented reflux (>0.5s) in the superficial or perforating veins in the trunk or tributary system underwent sclerotherapy with polidocanol foam (Aethoxyclerol R). Since there is important inter and intra observer variation and inherent physiological variations that do not directly influence ulcer healing, the caliber of the ...