2024年12月25日 · ITGA5 (Integrin Subunit Alpha 5) is a Protein Coding gene. Diseases associated with ITGA5 include Lung Cancer and Adult Spinal Cord Glioblastoma Multiforme. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Integrin Pathway.

Integrin alpha-5 is a protein that in humans is encoded by the ITGA5 gene. [5] The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This …

Elevated ITGA5 facilitates hyperactivated mTORC1-mediated progression of laryngeal squamous cell carcinoma via upregulation of EFNB2. ITGA5 Promotes Tumor Progression through the Activation of the FAK/AKT Signaling Pathway in Human Gastric Cancer.

2024年12月9日 · Title: TLN1 synergizes with ITGA5 to ameliorate cardiac microvascular endothelial cell dysfunction. Integrin alpha5 regulates motility of human monocyte-derived Langerhans cells during immune response.

2021年3月12日 · Our study demonstrated that ITGA5 may act as an essential regulator of tumor immune cell infiltration and a valuable prognostic biomarker in gastrointestinal tumors. Additional work is needed to fully elucidate the underlying mechanisms behind these observations.

Integrin subunit alpha 5 (ITGA5) encodes a protein belonging to the integrin alpha chain family, which plays a vital function in cell surface adhesion and signaling. ITGA5 has a deep connection with tumor invasion, tumor progression, and chemotherapy resistance (9, 10).

2021年3月12日 · Our study demonstrated that ITGA5 may act as an essential regulator of tumor immune cell infiltration and a valuable prognostic biomarker in gastrointestinal tumors. Additional work is needed to fully elucidate the underlying mechanisms behind these observations.

Integrin α5 (ITGA5) was involved in a variety of cancers. However, the role of ITGA5 in laryngeal squamous cell carcinoma (LSCC) remains unknown. The expression of ITGA5 and the corresponding clinicopathological parameters of LSCC patients the TCGA database.

Integrin alpha‐5 (ITGA5) is an integrin subtype that serves as a receptor for fibronectin, fibrinogen, and fibrillin‐1. The purpose of this study was to elucidate how ITGA5 expression plays a role in human non‐small cell lung cancer (NSCLC). Our clinical data, along with data retrieved from The Cancer Genome Database (TCGA), revealed that ...

2021年1月8日 · We found that integrin alpha5 (ITGA5) is expressed at high levels in bone metastases compared to non-bone metastases. Furthermore, multivariate analysis showed that ITGA5 expression in primary...