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Monitoring J-domain Proteins and Hsp70 Intera - JoVE Journal
7.1K Views. University of Groningen. Cognate J-domain proteins cooperate with the Hsp70 chaperone to assist in a myriad of biological processes ranging from protein folding to degradation. Here, we describe an in situ proximity ligation assay, which allows the monitoring of these transiently formed chaperone machineries in bacterial, yeast and ...
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For his role in the landmark discovery that molecular "chaperones" play a major role in protein folding, F. Ulrich Hartl was awarded the 2020 Breakthrough Prize in Life Sciences. See his full acceptance speech here https://youtu.be/ft6wh1ude7s?si=9MMZ5kK4M9rH8E-5&t=301 | Breakthrough
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