How do three billion base pairs of DNA fit into the nucleus of a cell? HMX - Harvard Medical School unravels the mystery. | Harvard University

Cancer cells are highly flexible and can change their behavior as they move through different environments in the body. New research shows that physical pressure around a tumor can trigger internal changes that push these cells away from rapid growth and toward a more invasive and treatment resistant state. These changes do not come from permanent DNA damage but from epigenetic shifts that alter how DNA is organized and accessed inside the cell nucleus. Using zebrafish models of melanoma, resear