Doc_Simplifies on Instagram: "Check out our PDFs — just click the link in Bio or DM me and start your journey to master medical concepts! . . Bilirubin is a yellow pigment formed during hemoglobin breakdown after RBC destruction. When bilirubin rises in blood, it leads to hyperbilirubinemia and may present as jaundice. Depending on the cause, it can be classified as prehepatic, hepatic, or posthepatic jaundice. Understanding the difference between unconjugated bilirubin (water insoluble, albumin